Di Pietro Health · Fort Lauderdale
Know exactly how your metabolism works.
The PNOE cardiometabolic analyzer delivers 23 precise biomarkers through a simple breath test — no blood draw, no lab wait. Resting and active testing, ordered and interpreted by a board-certified preventive cardiologist as part of your cardiac care.
Call us at (954) 523-4141
23
Biomarkers measured in a single breath test
10min
Resting test duration — non-invasive & comfortable
r≈.98
Correlation to gold-standard lab metabolic carts
#1
Predictor of cardiovascular mortality: your VO₂ Max
✓ Board-Certified Preventive Cardiologist
✓ No Blood Draw · No Lab Required
✓ Concierge Practice · Fort Lauderdale
✓ Clinically Validated Technology
Why It Matters Where You Get This Test
This isn’t a wellness amenity. It’s cardiology.
At a longevity center or fitness clinic
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Test is a standalone product — a number you leave with
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Results interpreted by a fitness coach or wellness staff, not a physician
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No integration with your cardiovascular risk profile, medications, or labs
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No cardiac monitoring during the active stress test
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Data sits in an app — no clinical follow-through
At Di Pietro Health
✓
Part of a preventive cardiology protocol — not a one-off test
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Ordered and interpreted by Dr. Di Pietro, D.O., FACC, FACOI — a board-certified cardiologist
✓
Results contextualized within your full cardiovascular risk picture, lab work, and medical history
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Active test includes cardiac stress monitoring — ECG-supervised exercise under physician oversight
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Translates directly into your care plan — exercise prescription, nutrition strategy, and ongoing monitoring
The Process
How the PNOE Breath Test Works
Indirect calorimetry is the gold standard for measuring metabolism. You breathe into a precision mask connected to the PNOE analyzer — it measures oxygen you consume and carbon dioxide you produce, breath by breath, in real time.
01
Arrive & Prepare
For resting tests, fast for 4–6 hours and avoid caffeine beforehand. For VO₂ Max testing, come in comfortable workout clothes prepared for a graded exercise stress test. Our team will walk you through everything.
02
Put on the Mask
A medical-grade silicone mask forms a precise seal over your nose and mouth, connected to the PNOE analyzer. For resting tests, you simply lie back and breathe normally for approximately 10 minutes.
03
The Test
The PNOE captures breath-by-breath oxygen and CO₂ data. The active VO₂ Max test pairs the breath analyzer with a cardiac stress test — progressive exercise on a treadmill or bike with continuous heart monitoring — until maximum effort is reached.
04
Your Results
Your 23-biomarker report is reviewed and interpreted by Dr. Di Pietro, who translates the data into a personalized nutrition, exercise, and cardiometabolic strategy tailored to your goals.
Testing Options
Two Tests. Complete Metabolic Picture.
Please note: PNOE metabolic testing is a standalone diagnostic service and is separate from a preventive cardiology consultation or office visit. If you are interested in a comprehensive cardiology evaluation with Dr. Di Pietro, please inquire about scheduling a consultation in addition to your metabolic test.
Resting Test
Resting Metabolic Rate (RMR)
$250
Most calorie estimates are guesses — built on population formulas that can be off by 20% or more. The PNOE measures exactly how many calories your body burns at rest, and what fuel it’s using to do it. It’s the difference between a plan built on averages and one built on your actual physiology.
✓
✓
✓
Active Test
VO₂ Max & Cardiometabolic Fitness
$350
VO₂ Max is the most powerful independent predictor of cardiovascular mortality — stronger than blood pressure, cholesterol, or smoking status. Knowing yours isn’t just for athletes. It’s essential preventive cardiology.
Includes a cardiac stress test — continuous ECG heart monitoring throughout graded exercise, performed under physician supervision.
✓
✓
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Book both tests together — Complete Metabolic Profile — $499
What We Measure
Key Biomarkers Your Report Includes
The PNOE analyzes how oxygen flows through your lungs, heart, and cells — producing actionable data on each system’s contribution to your metabolic health and longevity.
VO₂ Max
Aerobic Capacity
The maximum rate at which your body can use oxygen during exercise. The single strongest predictor of cardiovascular mortality and a key marker of biological age.
Fat-Max
Peak Fat Oxidation
The exercise intensity at which your body burns fat at its highest rate — a critical target for weight loss, metabolic flexibility, and endurance performance.
RMR
Resting Metabolic Rate
The exact number of calories your body burns at rest. Essential for building nutrition plans that actually match your physiology, not population averages.
VT1 / VT2
Ventilatory Thresholds
The intensity at which your breathing pattern shifts — defining your true Zone 2 ceiling and anaerobic threshold for precision training zone prescription.
RER
Respiratory Exchange Ratio
The ratio of CO₂ produced to O₂ consumed, revealing whether your body is burning fat or carbohydrates — and how metabolically flexible you are.
Bio Age
Metabolic Biological Age
A composite assessment of your metabolic and cardiovascular function compared to age and sex norms — an objective benchmark for tracking longevity interventions over time.
Ideal Candidates
Who Benefits from Metabolic Testing?
Weight Loss & GLP-1 Patients
If you’re on semaglutide or tirzepatide, or struggling with a stalled metabolism, RMR testing reveals whether adaptive thermogenesis has slowed your burn — and how to correct it without sacrificing muscle.
Endurance Athletes & Performers
Runners, cyclists, and triathletes receive precision heart rate zone prescriptions derived from their actual ventilatory thresholds — not wrist-based estimates — enabling smarter, more effective training.
Longevity & Preventive Cardiology
VO₂ Max is among the most powerful predictors of how long — and how well — you’ll live. Annual testing establishes your baseline, tracks improvement, and validates that your prevention program is working.
Hormone & Metabolic Health Patients
Thyroid dysfunction, hormonal shifts, and aging can profoundly alter metabolic rate and fat utilization. PNOE testing quantifies exactly what’s changed — providing objective data to guide hormonal optimization and nutrition.
Dr. Tiffany S.
Di Pietro
D.O., FACC, FACOI
Preventive Cardiologist
Internal Medicine Physician
“A VO₂ Max number from a gym is interesting. A VO₂ Max number interpreted by a cardiologist — in the context of your lipids, your coronary calcium score, your blood pressure, your family history — is a clinical tool. That’s the difference between a data point and a plan.”
— Dr. Tiffany S. Di Pietro, D.O., FACC, FACOI
Ready to know your real numbers?
Schedule your PNOE metabolic test at Di Pietro Health in Fort Lauderdale. Resting, active, or both — each test is a standalone service, reviewed and interpreted by a board-certified preventive cardiologist.
FREQUENTLY ASKED QUESTIONS
Dr. Di Pietro is always very helpful and will go out of her way to make sure I get the care needed. She is always accessible by phone should I have any questions, and she will follow up with me personally to make sure I am recovering well. Their office is very comfortable and has a home like feel. Much better than the normal doctor's office atmosphere. By far, the best doctor I have ever had!
PREVENTIVE
CARDIOLOGY
Preventive Cardiology, Metabolic Health & Cardiac Longevity All Under One Roof
CONCIERGE
INTERNAL MEDICINE
Patient-focused care, 24/7 in a comfortable environment
AESTHETICS
Personalized aesthetic care in a trusted medical setting
